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PDZ domains: More than just a glue.
P domains are part of a molecular scaffold that holds multiprotein signaling complexes together. It is generally believed that the role of PDZ domains is to position target ion channels, receptors, or other signaling molecules in correct spatial arrangement in relation to each other and to specialized regions of the cell (1–4). Two recent reports, one published in Cell (5) and another in this i...
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ژورنال
عنوان ژورنال: Nature Cell Biology
سال: 2002
ISSN: 1465-7392,1476-4679
DOI: 10.1038/ncb0802-e196